Berikut adalah daftar nama pemain sepakbola Mali di Piala Afrika 2021 lengkap usia dan klub saat ini.
| No | Posisi | Nama | Usia | Klub Saat Ini |
|---|---|---|---|---|
| GK | Djigui Diarra | 26 | Young Africans | |
| 1 | GK | Ibrahim Mounkoro | 31 | Mazembe |
| 22 | GK | Ismael Diawara | 27 | Malmö |
| 16 | GK | Mohamed Niare | 26 | Stade Malien |
| 2 | DF | Hamari Traoré | 29 | Rennes |
| 15 | DF | Mamadou Fofana | 23 | Amiens |
| 17 | DF | Falaye Sacko | 26 | Vitória de Guimarães |
| 5 | DF | Boubakar Kouyaté | 24 | Metz |
| 3 | DF | Charles Traoré | 30 | Nantes |
| 13 | DF | Senou Coulibaly | 27 | Dijon |
| 12 | DF | Moussa Sissako | 21 | Standard Liège |
| 21 | MF | Adama M. Traoré | 26 | Sheriff Tiraspol |
| 7 | MF | Moussa Doumbia | 27 | Reims |
| 14 | MF | Adama N. Traoré | 26 | Hatayspor |
| MF | Moussa Djenepo | 23 | Southampton | |
| 4 | MF | Amadou Haidara | 23 | RB Leipzig |
| 8 | MF | Diadie Samassékou | 25 | 1899 Hoffenheim |
| 23 | MF | Aliou Dieng | 24 | Al Ahly |
| 18 | MF | Rominigue Kouamé | 25 | Troyes |
| 6 | MF | Mohamed Camara | 22 | Red Bull Salzburg |
| 10 | FW | Kalifa Coulibaly | 30 | Nantes |
| 9 | FW | El Bilal Touré | 25 | Reims |
| FW | Ibrahima Koné | 22 | Sarpsborg 08 | |
| 20 | FW | Lassine Sinayoko | 22 |  Auxerre |